Table of Contents
- The differences between the individual corona tests on the market
- The test types in direct comparison
- The corona antigen test explained
- Order SARS-CoV-2 antigen tests
- The corona antibody test
- Order SARS-CoV-2 antibody tests
Overview of the corona tests
Since the beginning of the pandemic, not only is there high pressure after a corona vaccine, but also looked for ways to quickly and reliably detect the virus in infected peopleto break the chains of infection. There are now three test procedures available, all of which are important and are justified: however, they can only provide reliable information if they are used correctly.
We would like to explain briefly and simply which COVID-19 tests are available, when they should be used and what the test result really says.
PCR stands for Polymerase Chain Reaction (Polymerase chain reaction and describes a test method in which precisely defined test methods are present in the samplee SARS-CoV-2 virus DNA fragments be multiplied with a special enzyme. These can then can be detected with the help of a special device. The PCR method makes it possible to to make a statement about the presence of the SARS-CoV-2 virus in the smear and about the viral load.
The PCR test we offer from SD Biosensor from South Korea is one of the best in the world and we will be happy to make you an individual offer on request.
The antigen test also enables direct evidence of SARS-CoV-2, however, a certain surface protein of the virus is detected here. In contrast to the PCR test, the antigen test can be carried out directly on site and delivers the test result within a few minutes. The advantage of the antigen test is that it very easy to do and provides quick test results, so that a decision can be made directly at the point-of-care on how to proceed.
The antibody test differs from the PCR and antigen tests in that it not the virus itself, but the body's immune response to infection with SARS-CoV-2. Since the formation of antibodies, which this rapid test can detect, does not begin until a few days at the earliest - usually even later - it is not suitable for detecting an acute infection. It is used to determine whether the patient has already survived an infection with SARS-CoV-2.
The different corona test methods in comparison
|PCR test||Antigen test||Antibody test|
|What is proven?||Virus genetic material||Protein fragments of the virus||Antibodies to the virus|
|Direct pathogen detection||Direct pathogen detection||Immune response of the patient|
|At what stage of the infection does the test work??||During acute infection||During acute infection||In the final phase of the infection or if the infection has already been overcome|
|Which sample material is required?||Nasopharyngeal swab||
Depending on the test:
|Where is the test carried out??||In the laboratory||At the point of care z. B. directly in the doctor's office, in the hospital or in the fever clinicz)||At the point of care z. B. directly in the doctor's office, in the hospital or in the fever clinicz)|
|How long does it take to get the result??||Including transport to the laboratory approx. 24 - 48 hours||Approx. 15-30 minutes||Approx. 10-20 minutes|
|For what purpose is the test carried out??||To confirm a suspected diagnosis||To control contacts and to identify infected people without symptoms that are highly contagious||For proof of a previous infection|
Rapid antigen test
With this rapid corona test, an acute coronavirus infection is to be confirmed by direct pathogen detection. The SARS-CoV-2 test is carried out with different sample material, depending on the manufacturer. Most rapid tests require nasopharyngeal swabs, but antigen tests are now also available that can be performed with saliva, sputum or even with stool samples. The test is carried out directly at the point of care - e.g. B. in the doctor's office, in the hospital or by trained staff in e.g. nursing homes,
A classic test kit for detection by means of a nasopharynx swab includes a sterile swab as well as an extraction buffer and a test cassette. The principle and implementation of these rapid antigen tests are fundamentally very similar - the main difference lies above allin specificity and sensitivity as well as in the amount of work involved in performing the test. The exception is here Rapid tests done on saliva. These tests work particularly wellfor patients who cannot tolerate a smear - such as B. small children, people with disabilities or the elderly.
The Genbody Inc. Covid-19 Ag antigen test from the South Korean manufacturer Genbody Inc. enables a particularly uncomplicated test execution and delivers a reliable test result in just 10 to 15 minutes due to its high specificity and high sensitivity. The test is also listed at the BfArM.
The greatest potential with this test principle lies in the rapid identification of infected people who do not show any COVID-19 symptoms, but have, for example, had contact with people who have been proven to be infected. A quick assessment of the infection status is possible here and it can be preventedthat an unnoticed COVID-19 infection leads to a widespread spread of the virus.
All of our SARS-CoV-2 antigen rapid tests listed are BfArM-listed..
Rapid antibody test
With this rapid test, patients can be identified who have already formed antibodies against SARS-CoV-2. This not only plays a role in clearing up chains of infection, but can also be of interest to patients who are in a late stage of the infection. In these patients, pathogens are often no longer detectable in the nasopharyngeal space. In contrast to the other tests, the rapid test is carried out with a blood sample.
A negative result does not rule out an acute infection in the rapid antibody test, but only means that there has not yet been an immune response. With such an immune response and the formation ofon IgG and IgM antibodies can be expected after a few days at the earliest - for most patients it takes even longer.
This coronavirus test is therefore not suitable for detecting a current infection with the novel coronavirus.
Here, too, the rapid tests from the different manufacturers are very similar in terms of test execution and the test principle. In addition to the test cassette, a test kit contains a pipette for applying the blood sample and a buffer solution.
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